Establishment of human induced pluripotent stem cell line from dermal fibroblasts of a healthy individual
نویسندگان
چکیده
منابع مشابه
Generation of human induced pluripotent stem cells from dermal fibroblasts.
The generation of patient-specific pluripotent stem cells has the potential to accelerate the implementation of stem cells for clinical treatment of degenerative diseases. Technologies including somatic cell nuclear transfer and cell fusion might generate such cells but are hindered by issues that might prevent them from being used clinically. Here, we describe methods to use dermal fibroblasts...
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Multiple sclerosis (MS) is an autoimmune disease which affects myelin in the central nervous system (CNS) and leads to serious disability. Currently available treatments for MS mainly suppress the immune system. Regenerative medicine-based approaches attempt to increase myelin repair by targeting endogenous progenitors or transplanting stem cells or their derivatives. Fingolimod exerts anti-inf...
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ژورنال
عنوان ژورنال: Stem Cell Research
سال: 2020
ISSN: 1873-5061
DOI: 10.1016/j.scr.2020.101762